Legapas®

Contraindications/Cautions:

Do not use with abdominal pain, nausea, fever, vomiting, hemorrhoids. Do not use if taking thiazide diuretics, corticosteroids, licorice root, or other drugs that may aggravate electrolyte imbalance. Do not use in pregnancy or breastfeeding.
Do not use within 2 hours of another medicine. Use caution in a patient with a kidney disorder or who are taking heart medications. Reduce dose or discontinue use if abdominal cramps, spasms, and/or pain occur. 

Side effects:

Very rarely cramp-like gastrointestinal symptoms; in these cases, the dose will have to be reduced. Harmless discolouration of your urine may occur. Prolonged use or use of higher doses (abuse) may cause disturbances of the water and electrolyte balance. Diarrhea may lead to potassium loss in particular. Potassium loss, in turn, may give rise to disorders of heart function and muscle weakness, especially if cardiac glycosides (drugs that strengthen the heart muscle), diuretics (drugs that increase urinary output), and/or cortisone and cortisone-like drugs (adrenal cortical steroids) are being taken concomitantly. Prolonged use may lead to excretion of protein and blood in the urine. Patients may also experience discolouration of the intestinal mucosa (pseudomelanosis coli), which usually resolves upon discontinuation of the product.

Interactions:

Chronic use or abuse may lead to potassium deficiency and thus increase the effects of certain drugs that strengthen the heart muscle (cardiac glycosides) and interfere with the effects of drugs for heart rhythm disturbances (antiarrhythmics). Potassium loss may be increased by the concomitant use of certain drugs that increase urinary output (diuretics), cortisone and cortisone-like drugs (corticosteroids) or licorice root.